Frequently Asked Questions (FAQs)

What support services does Alnylam Assist™ provide?

Alnylam Assist™ provides patients with product support services, including:

  • Benefit verification for ONPATTRO
  • Education about the prior authorization, claims, and appeals processes
  • Financial assistance program enrollment for eligible patients*
  • Information about hATTR amyloidosis and ONPATTRO 
  • Ordering product

*Patients must meet specified eligibility criteria to qualify for assistance. Alnylam reserves the right to make eligibility determinations and to modify or discontinue any program at any time.

Where can I find more materials about ONPATTRO and Alnylam Assist™?

Support and educational materials about ONPATTRO and Alnylam Assist™ can be found on this site.

Who makes up the Alnylam Assist™ team?

Case Managers are experienced in helping individuals get started on treatment and providing ongoing support. They will tailor their method of communication based on what works best for the individual.

Field Reimbursement Directors (FRDs)  provide education about coverage, coding, and reimbursement for ONPATTRO.  FRDs are knowledgeable about ONPATTRO billing and coding requirements.

Patient Education Liaisons (PELs) have backgrounds in nursing, and are experienced in educating individuals and their families about matters related to hereditary ATTR (hATTR) amyloidosis. PELs can help patients in a variety of ways, including providing disease and product education, connecting patients to additional resources, and answering questions about treatment with ONPATTRO. 

  • The Purpose of Alnylam Patient Education Liaisons (PELs) is to provide education to patients, their families, and caregivers 
  • PELs are employees of Alnylam Pharmaceuticals and do not provide medical advice 
  • All diagnosis and treatment decisions should be made by the treating physician and their patients

What is
Alnylam Assist™?

Alnylam Assist™ includes Case Managers, Patient Education Liaisons, and Field Reimbursement Directors who provide support to patients prescribed Alnylam therapies.  This support includes: verification of insurance benefits, coverage and reimbursement education, financial assistance support for eligible patients, and disease and product education.  Each member of our team is assigned to specific geographic regions to work with patients, their caregivers, healthcare providers, and insurance companies to support patients throughout treatment on 

ONPATTRO® (patisiran).

How do I enroll my patient in the Alnylam Assist™ program?

There are three ways to enroll your patients:

  1. Complete the electronic Start Form
    • You will receive an auto-generated confirmation after submission to let you know we have received the Start Form and are initiating support
    • You and your patient will each receive a phone call from his or her case manager within 1-2 business days of receipt
  2. Download the writable PDF version—which can be completed in English, Español,  Português Europeau,  and Português Brasileiro—and fax the completed Start Form to Alnylam Assist™ at 833-256-2747
    • You and your patient will receive a phone call from an Alnylam Case Manager within 2 business days of receipt
  3. Begin filling out the DocuSign form and DocuSign will send to your patient to complete
    • Once you have finished your portion of the Start Form and provided an eSignature, it will be emailed to your patient so they can verify the information and fill out any remaining fields
    • Both you and your patient will receive notification via email when the completed Start Form has been submitted to Alnylam Assist™
    • An Alnylam Case Manager will reach out to you and your patient within 2 business days of receiving the completed Start Form
    • For help submitting the DocuSign form, download our DocuSign Instructions.